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It is versatile, device-independent and based on opened security standards. 
OpenOTP provides fine-grained user identity and access management (IAM), one-time passwords authentication technologies (OTP), Universal Second Factor (U2F) and extensive authentication policies for your AD / LDAP users. 
It is enterprise-ready with strong support for high-availability, load-balancing, multi-tenancy, cloud-readiness, geolocalization, delegated administration and much more.

OpenOTP Two-Factor Authentication

OpenOTP plugin Enable two-factor authentication for your admins and/or users The plugin will transparently handle any OpenOTP Login Mode including, LD …

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WordPress Strong Authentication lets you authenticate users with a second 
factor of possession.
Only if the user is able to provide this second factor, he is allowed to login. 
Such a second factor can be an OTP display card, an OTP hardware token, a Yubikey, 
a smartphone App like the Google Authenticator or access to an mobile phone 
to receive an SMS or access to an email account.
The use then needs to authenticate with his wordpress password and in addition with 
a code, generated by his device or sent via email or SMS.
All the devices are managed in the backend (privacyIDEA)[http://privacyidea.org], the Strong Authentication 
plugin forwards authentication requests to this backend, which you can easily run 
on the same machine or anywhere in your network.
<h3>Configuration</h3>
Please add at least a hostname or IP address of your backend server privacyIDEA. 
You need to enter the hostname together with the protocol and the port, if it is 
not a standard port. 
If you are using self signed certificates, you should disable the verification of hostname and peer.
Please note: You need to have the same users in the LinOTP server. 
You can achieve this by configuring an SQL Resolver and presetting this to 
Wordpress.
<h3>Troubleshooting</h3>
If you misconfigured the plugin, you might not be able to authenticate anymore!
So it is always a good idea to add some users to the “excluded users” list. 
These users will be able to authenticate without a second factor and 
even if the authentication server should be down.
Another possibility is to disable the plugin by removing or renaming the 
plugin directory. 
In this case is will fall back to the old wordpress passwords.

WordPress Strong Authentication

Wordpress Strong Authentication lets you authenticate users with a second

OpenOTP Two-Factor Authentication vs WordPress Strong Authentication