Luigi Cavalieri

RedBrick is able to block most of the automated spam comments a WordPress blog receives daily.
It is based upon a score system that ensures spam comments are blocked as soon as possible, so as to minimise the number of checks each comment must go through. When in doubt, RedBrick always holds the comment in the moderation queue. Comments identified as spam, however, never reach the database.
As a last resource in discerning the kind of comment under examination, RedBrick takes account also of the comment author’s history.
The plugin is designed to work on low-to-medium traffic blogs.

RedBrick

Simple anti-spam plugin for WordPress blogs.

MikesPickz

MP Spam Be Gone is the simplest, most effective Spam blocker without difficult CAPTCHA responses needed by the user. This plugin was inspired by some of the best Anti-Spam plugins available on WordPress.
Inspirations: 
Spam Free WordPress by Todd Lahman, LLC 
Growmap Anti Spambot Plugin by Andy Bailey 
Simple Trackback Validation with Topsy Blocker by Tobias Koelligan
This plugin has aspects from all of the above mentioned plugins to form the most complete and dead simple Anti Spam plugin on WordPress. This plugin doesn’t write anything to your database while preventing comment spam and trackback spam.
From Growmap Anti Spambot Plugin, I used the concept of having a checkbox display to the user in order to prevent automated Spam. To me this is the best way (and least intrusive) to completely prevent automated spam from ever even being written to the database in the spam que. It is physically impossible to get a false positive, since you either checked the button or not. The flaw with this plugin is that it does not work with Javascript disabled.
To combat that flaw, I use the copy and paste password fields from the Spam Free WordPress plugin. These fields are in a <code><noscript></code> tag, and only appear if Javascript is disabled. Unlike, the Spam Free WordPress plugin, these passwords are generated on the fly and never stored in the database.
These plugins primarily stop comment spam. In order to stop trackback spam, I added the IP address check, URL check, and Topsy check functions from Simple Trackback Validation with Topsy Blocker. If a trackback is identified as spam because of the IP address or Topsy, it is deleted and never written to the database. If a trackback is identified as spam because of the URL, it is marked as spam and sent to the Spam que. The reason that these are not automatically deleted, is because it is possible that the referring page is using a shortlink and therefore the full URL would not appear on the page in the first place.
When combined, this plugin will stop all automated spam and trackbacks.
It is intended to replace the above plugins.
You can’t find a plugin simpler than this – set it and forget it. No options = no modifications to the database.

MP Spam Be Gone

MP Spam Be Gone is the simplest, most effective Spam blocker.

RedBrick vs MP Spam Be Gone