You can press CTRL+S in ANY browser to save the work you’re working with, including posts and pages.
Some features:
<ul>
<li>Saves your current work by pressing CTRL+S</li>
<li>Works in all browsers (thanks <a href="http://www.openjs.com/" title="Open JS" rel="nofollow ugc">Binny V A</a>)</li>
<li>No jQuery</li>
<li>Made in Sweden</li>
</ul>

The Saver

This plugins allows you to publish your posts/pages and update your files in the admin panel by pressing CTRL+S.

Sjeiti

Mattia Trapani

This plugin lets you save your posts, pages, theme and plugin files, widgets, menus, etc. in the most natural way: pressing Ctrl+S (or Cmd+S on Mac).
I’ve coded this plugin because I was tired of pressing Cmd+S and then realize Chrome was trying to save the whole webpage
After coding this up, I’ve found in the plugin directory two plugins that did the same thing, but each one had some flaws that convinced me to publish mine.
This plugin loads a small Javascript file (minified if not WP_DEBUG). The Javascript checks the contents of any admin page for save buttons.
It is also so smart that saves as draft unpublished posts/pages and updates the ones that are already public.
Also adds a little tooltip on the buttons that can be “clicked” with Ctrl+S or Cmd+S.

Save with keyboard

Installed, no setup, just works - Ctrl/S at at last!

Perfect - Just works!

Works like a charm! Can't believe this feature is still not built-in. Thank you

Finally a solution to an annoying issue!

This plugin works as described and is really handy for those of us who want to keep our hands on the keyboard for maximum productivity. Much appreciated.

Still works, WP 6.0.2

Save everything in the most natural way by pressing Ctrl+S (or Cmd+S on Mac).

The Saver vs Save with keyboard