You can press CTRL+S in ANY browser to save the work you’re working with, including posts and pages.
Some features:
<ul>
<li>Saves your current work by pressing CTRL+S</li>
<li>Works in all browsers (thanks <a href="http://www.openjs.com/" title="Open JS" rel="nofollow ugc">Binny V A</a>)</li>
<li>No jQuery</li>
<li>Made in Sweden</li>
</ul>

The Saver

This plugins allows you to publish your posts/pages and update your files in the admin panel by pressing CTRL+S.

mortalis

The Pre button toggles the preformatted style on the selected text or the current line (applies <code><pre></code> tag to blocks). 
The Code button toggles the code style on the selected text or the current word (applies <code><code></code> tag to inline elements).
The default shortcuts for the buttons are:
<ul>
<li>Ctrl+Q – Pre</li>
<li>Ctrl+D – Code</li>
</ul>
In the admin Settings submenu it’s possible to change these shortcuts. 
Press a key combination in the text fields with the Ctrl key included and the text will be filled automatically. Or you can type it manually.
Some combinations may conflict with the default editor or browser shortcuts. 
So check them on your instance.
You may use these types of shortcuts:
<ul>
<li><code>Ctrl+B, .., Z (except AXCV)</code></li>
<li><code>Ctrl+0, .., 9</code></li>
<li><code>Ctrl+[symbols] (-=`[];'\/,.)</code></li>
<li><code>Ctrl+F1, .., F12</code></li>
<li><code>Ctrl+Pad0, .., Pad9</code></li>
<li><code>Ctrl+Pad/, Pad*, Pad+, Pad.</code></li>
<li><code>Ctrl+Shift+...</code></li>
<li><code>Ctrl+Alt+...</code></li>
<li><code>Ctrl+Shift+Alt+...</code></li>
</ul>
This plugin GitHub repository: https://github.com/mortalis13/tinymce-code-formatting.

TinyMCE Code Formatting

Nice and clean made plugin. Thank you!

Adds the Pre and Code buttons to the TinyMCE toolbar with customizable shortcuts

The Saver vs TinyMCE Code Formatting