Max Cutler

Uses PHP’s output buffering to buffer XML-RPC responses and strip superfluous whitespace.
Plugins, themes, and any other files executed during the WordPress load process can unintentionally emit whitespace, 
such as by including a newline character after an explicit closing “?>” PHP tag instead of letting PHP auto-close the 
file.

XML-RPC De-whitespacer

Removes leading and trailing whitespace from XML-RPC responses that can break some XML-RPC clients.

Samuel Aguilera

Stops abuse of your site’s XML-RPC by simply removing some methods used by attackers. While you can use the rest of XML-RPC methods.
This is more friendly than disabling totally XML-RPC, that it’s needed by some plugins and apps (I.e. Mobile apps or some Jetpack’s modules).
<ul>
<li>The original one.</li>
<li>Simple and effective.</li>
<li>No marketing buzz.</li>
<li>Maintained and updated when needed since 2014.</li>
<li>100% compliant with WordPress coding standards which makes it fail safe.</li>
<li>60,000+ active installations can’t be wrong.</li>
</ul>
If you’re happy with the plugin <a href="https://wordpress.org/support/plugin/disable-xml-rpc-pingback/reviews/?filter=5" rel="ugc">please don’t forget to give it a good rating</a>, it will motivate me to keep sharing and improving this plugin (and others).
<h4>Features</h4>
Removes the following methods from XML-RPC interface.
<ul>
<li>pingback.ping</li>
<li>pingback.extensions.getPingbacks</li>
<li>X-Pingback from HTTP headers. This will hopefully stops some bots from trying to hit your xmlrpc.php file.</li>
</ul>
<h4>Requirements</h4>
<ul>
<li>WordPress 3.8.1 or higher.</li>
</ul>

Disable XML-RPC Pingback

Gran trabajo Samuel, en combinación con algunas reglas de htaccess hace un trabajo fantástico.

Fantástico plugin, imprescindible

Stops abuse of your site's XML-RPC by simply removing some methods used by attackers. While you can use the rest of XML-RPC methods.

XML-RPC De-whitespacer vs Disable XML-RPC Pingback